Send us a text with a question or thought on this episode ( We cannot replay from this link)
Dr. Abhishek Mangeshikar explores how endometriosis severity varies globally, highlighting the interplay between genetics, environmental factors, and healthcare access. While genetic components exist in endometriosis development, expression is influenced by epigenetics including diet, stress, and environmental conditions that determine disease progression patterns.
• Endometriosis has a genetic component, but gene expression depends on epigenetic factors
• Environmental factors, diet, hormones, and physiological stress influence disease expression
• Healthcare access significantly impacts observed disease severity across regions
• Lower-income countries typically see more advanced disease due to delayed diagnosis
• Early intervention in higher-income countries often prevents progression of certain disease types
• More diverse, multicultural studies are needed to understand global endometriosis patterns
Send your endometriosis questions by using the link in the description, emailing contact@endobattery.com, or visiting the endobattery.com contact page.
Website endobattery.com
Quick Connect Introduction
Speaker 1
0:00
Life
moves
fast
and
so
should
the
answers
to
your
biggest
questions
.
Welcome
to
EndoBattery's
Quick
Connect
,
your
direct
line
to
expert
insights
Short
,
powerful
and
right
to
the
point
.
You
send
in
the
questions
,
I
bring
in
the
experts
and
in
just
five
minutes
you
get
the
knowledge
you
need
.
No
long
episodes
,
no
extra
time
needed
,
and
just
remember
expert
opinions
shared
here
are
for
general
information
and
not
for
personalized
medical
advice
.
Always
consult
your
provider
for
your
case-specific
guidance
.
Got
a
question
?
Send
it
in
and
let's
quickly
get
you
the
answers
.
Speaker 1
0:34
I'm
your
host
,
alana
,
and
it's
time
to
Dr. Mangeshkar Expert Introduction
Speaker 1
0:37
connect
.
Today
I'm
joined
by
my
expert
guest
,
dr
Abhishek
Mangeshkar
,
a
leading
endometriosis
specialist
and
minimally
invasive
gynecologic
surgeon
from
Mumbai
,
india
.
He's
the
founder
and
director
of
the
Indian
Center
for
Endometriosis
and
has
extensive
expertise
in
treating
deep
infiltrating
endometriosis
through
advanced
laparoscopic
techniques
,
with
training
in
neuropelviology
and
thousands
of
complex
surgeries
performed
.
Dr
Mings
is
passionate
about
a
patient-first
,
multidisciplinary
approach
to
care
.
I'm
thrilled
to
have
him
join
me
today
to
share
his
expertise
.
Let's
dive
Cultural Impacts on Endometriosis
Speaker 1
1:15
in
.
In
your
opinion
,
do
you
feel
like
you
see
,
endometriosis
and
its
severity
vary
based
on
culture
,
geographical
location
or
the
different
foods
and
different
cultures
?
Speaker 2
1:26
We
do
know
that
endometriosis
has
definitely
got
a
genetic
component
to
it
,
so
there
is
a
gene
passed
down
.
But
whether
that
gene
expresses
itself
has
a
lot
to
do
with
epigenetics
and
probably
environmental
dietary
hormonal
you
know
stress
,
and
I
don't
mean
just
mental
stress
.
Speaker 2
1:48
It
could
be
physiological
,
inflammatory
stress
that
causes
whether
the
disease
grows
,
how
it
expresses
itself
and
how
aggressively
it
can
grow
and
spread
.
That
determines
these
certain
phenotypes
of
disease
.
The
short
answer
is
we
don't
know
yet
.
There
should
be
a
lot
more
studies
going
on
about
this
,
but
it's
very
difficult
to
get
a
widespread
diaspora
,
multicultural
Healthcare Access and Disease Progression
Speaker 2
2:14
,
multidiverse
population
to
study
.
Speaker 1
2:18
Yeah
,
and
I
would
imagine
that
part
of
that
comes
down
to
access
to
care
too
,
because
I
know
in
different
parts
of
the
world
care
is
not
really
accessible
for
a
lot
of
people
,
so
I
think
it's
probably
hard
to
really
get
a
good
study
based
off
of
.
What
we
currently
have
is
like
care
is
not
accessible
for
a
lot
of
people
in
a
first
world
country
,
let
alone
a
third
world
country
.
Speaker 2
2:42
Actually
I
think
you
kind
of
nailed
it
or
you
hit
the
nail
on
the
head
,
because
when
you
would
see
more
advanced
disease
from
the
lower
economy
populations
compared
to
the
US
or
Europe
or
Australia
,
where
they
would
get
early
primary
care
,
so
you
know
they
would
have
the
cysts
dealt
with
earlier
and
the
people
disease
which
is
more
complex
and
very
few
people
can
treat
that
kind
of
gets
left
behind
and
sheltered
through
,
whereas
in
the
other
populations
like
India
,
the
Middle
East
,
africa
,
asia
,
they
would
not
have
such
early
access
to
care
or
there
would
be
delays
in
diagnosis
and
treatment
.
So
you
would
see
more
advanced
disease
in
those
cases
,
especially
when
it
had
to
do
with
cysts
in
the
ovaries
,
affecting
the
tubes
or
even
uterine
disease
.
That's
being
allowed
to
progress
because
of
the
inertia
of
the
medical
systems
in
those
countries
.
Episode Closing and Contact Info
Speaker 1
3:34
That's
a
wrap
for
this
Quick
Connect
.
I
hope
today's
insights
helped
you
move
forward
with
more
clarity
and
confidence
.
Do
you
have
more
questions
?
Keep
them
coming
,
send
them
in
and
I'll
bring
you
the
expert
answers
.
You
can
send
them
in
by
using
the
link
in
the
top
of
the
description
of
this
podcast
episode
or
by
emailing
contact
at
endobatterycom
or
visiting
the
endobatterycom
contact
page
.
Until
next
time
,
keep
feeling
empowered
through
knowledge
.