Exploring Personalized Hormone Solutions with Kate Boyce, BCPA

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Exploring Personalized Hormone Solutions with Kate Boyce, BCPA
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Dive headfirst into the complex world of hormone replacement therapy in this part 2 episode with Kate Boyce, of Endo Girls Blog as we strip away the one-size-fits-all approach to HRT for conditions like endometriosis and adenomyosis. This discussion isn’t about blanket solutions; instead, it’s a deep exploration into the personalized nature of treatment, from the role of progesterone to the surprising impact of testosterone. We’re challenging the status quo and simplifying the process to focus on what really matters – your unique health journey.

Navigating the minefield of hormone balance and the risks of HRT can be daunting, but we’re here to guide you through it with the latest insights and research. We’ll tackle the body’s remarkable but complex survival mechanisms and the importance of symptom-based treatment adjustments. And let’s not shy away from the controversies and risks – knowledge is power, and we’re empowering you to partner with healthcare providers who truly understand your needs.

We round up the discussion by addressing the broader health implications of HRT, such as the potential link to dementia prevention, and dissect the ongoing debates within the medical community. By sharing personal anecdotes and critically analyzing the research, we’re cutting through the noise to bring you evidence-based, accessible information. This episode is more than just a discussion; it’s a call to action for informed consent, education, and advocacy in the evolving field of women’s health. Join us for an episode that is as thought-provoking as it is informative, with the goal of bringing you to the forefront of your health decisions.

https://endogirlblog.com/

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Hormone Replacement Therapy for Endometriosis

Speaker 1
0:03

Welcome

to

Indobattery
,

where

I

share

about

my

endometriosis

and

adenomyosis

story

and

continue

learning

along

the

way
.

This

podcast

is

not

a

substitute

for

professional

medical

advice

or

diagnosis
,

but

a

place

to

equip

you

with

information

and

a

sense

of

community
,

ensuring

you

never

have

to

face

this

journey

alone
.

Join

me

as

I

navigate

the

ups

and

downs

and

share

stories

of

strength
,

resilience

and

hope
.

While

navigating

the

world

of

endometriosis

and

adenomyosis
,

from

personal

experience

to

expert

insights
,

I'm

your

host
,

elana
,

and

this

is

Indobattery

charging

our

lives

when

endometriosis

drains

us
.

Welcome

back

to

Indobattery
.

Grab

your

cup

of

coffee

or

your

cup

of

tea

and

join

Kate

Poisoni

from

Indogirl

blog

at

the

table

as

we

continue

our

discussion

on

hormones
.

This

is

where

we

left

off

and

where

we're

going
.

The

other

seed

of

this

is

that

the

progesterone
.

We've

talked

about

this
.

You're

not

a

progesterone

person
,

but

then

there's

other

people

in

the

progesterone

camp

who

find

significant

benefits

for

them

and

how

they

feel
.

What

are

your

thoughts

on

that
?

Like

with

any

of

them
.

Speaker 2
1:14

I'd

see

that

as

well
.

People

who

are

like

well
,

I

feel

so

much

better

on

the

progesterone
.

But

I

will

say

that

typically

changes

once

they

get

their

testosterone

levels

right
.

From

a

non-clinical

perspective

here
,

just

as

a

patient

advocate

perspective

and

working

through

that

typically

it's

like

oh
,

the

progesterone

was

good

enough

to

help

me

sleep
,

or

a

good

enough

to

help

with

anxiety
,

but

oh
,

magically

that

anxiety

went

away

when

my

testosterone

levels

got

better
.

Oh
,

everything

else

calmed

down

when

my

testosterone

levels

got

better
.

This

isn't

really

that

uncommon

because

you'll

see

that

a

lot

of

providers
,

once

you've

had

a

hysterectomy
,

they

won't

even

prescribe

progesterone

with

hormone

replacement

therapy
.

It

seems

to

be

only

pushed

by
.

The

wellness

space

or

the

holistic

places

are

the

only

ones

that

ever

seem

to

be

pushing

the

progesterone
.

That's

because

way

back

in

the

day

I

don't

know

if

you

remember

this

book

it

was

like

what

your

Doctor

Won't

Tell

you

About

Minipause
.

I

don't

know

if

you

remember

that
.

Speaker 2
2:12

My

mom

had

bought

that

in

the

90s

it

was

this

provider

that

pushed

progesterone

cream
.

Everybody

in

the

wellness

space

just

clung

to

that
.

It

has

stuck

as

this
.

Progesterone's

like

this

woman

hormone

that's

needed

for

rest

and

calmness

and

sleep
,

whatever
,

like

estrogen
.

We

don't

continue

to

make

it

forever
.

Speaker 2
2:37

Progesterone's

genuine
.

Its

primary

purpose

really

does

have

to

do

with

pregnancy
.

It's

one

that
,

like
,

I

don't

want

to

say

it

doesn't

have

a

role
,

but

it's

the

one

that

I

see

people

ever

need

the

least
.

But

it's

the

most

accessible

because

it's

pushed

the

most
,

especially

in

the

wellness

space

and

it's

so

easy

to

access
.

It

seems

to

be

the

most

popular
,

and

then

people

will

see

maybe

a

couple

benefits

and

be

like
,

oh
,

that's

it
,

that

was

good
,

that's

what

I

needed

and

that's

fine

if

that's

where

they

want

to

stay
.

Speaker 2
3:08

But

I

also

let

people

know

that
,

since

there

are

side

effects

with

progesterone

that

seem

to

be

pretty

intense

for

a

lot

of

people

the

inability

to

lose

some

way
,

a

lot

of

water

retention
,

too

sleepy

it

just

for

me

too
,

like

I

cannot

stay

on

progesterone

and

it

actually

does

interact

with

our

androgen

receptors

and

so

a

lot

of

the

time
,

once

you

know

someone

gets

their

hormones

figured

out

with

estrogen

and

testosterone
,

they'll

come

off

the

progesterone
,

they're

like

okay
,

I

didn't

even

need

that
.

That's

just

kind

of

how

I

feel

with

it
,

and

especially

working

with

providers

who

don't

even

utilize

it

if

there's

already

been

a

hysterectomy
.

Of

course
,

if

someone

has

a

uterus
,

they

absolutely

have

to

be

on

it

if

they're

on

estrogen
.

Speaker 2
3:46

There's

no

question
,

right

the
,

you

have

to

induce

a

period
,

you

have

to

shed

the

lining

of

the

uterus
,

otherwise

you

risk

endometrial

hyperplasia
,

which

can

then

lead

to
,

you

know
,

endometrial

cancer
.

So

I

definitely

get

scared

when

I

see

people

who

are

like

well
,

I'm

on

estrogen
,

but

I

won't

take

progesterone

and

I

haven't

had

a

hysterectomy
,

oh

God

please

just

go

to

any

doctor

Any

doctor
.

Speaker 1
4:06

Go

to

the

ER

now
.

Speaker 2
4:09

Please

do

not

do

that
.

And

that

part

is

scary
.

But

when

it

comes

to

you

know

you've

already

had

the

hysterectomy

it's

like

it

gets

once

again
.

It's

nuanced

If

somebody

wants

to

be

on

it

and

it's

not

expensive

whatever
.

But

if

someone's

going

to

some

pricey

wellness

coach

that's

putting

them

on

a

progesterone

cream
,

that's

when

I
,

like

raise

the

eyebrow
,

you

know
,

as

their

advocate
,

cause

I'm

like
,

okay
,

well
,

let's

take

a

better

look

at

this
,

let's

take

a

step

back
,

right
.

That

is

just

often

the

case

that

I

see

with

the

testosterone
.

Speaker 2
4:35

Once

the

testosterone

gets

leveled

out
,

right

with

estrogen
,

I

see

a

lot

of

these

patients

I

work

with

being

like
,

okay
,

I'm

coming

off

the

progesterone
.

I

feel

like

the

consensus

with

us

is

let's

be

on

the

least

amount

of

stuff

possible
,

right
.

Same

with

supplements

right
.

I

just

was

like

I

want

off

so

tired
.

Same
.

Like

what

can

I

want

to

be

on

the

least

amount

of

everything
?

So

okay
.

Speaker 2
4:55

Fortunately
,

I

get

80

to

100

milligrams
,

depending

on

levels

of

testosterone

pellet

every

12

to

13

weeks

and

that's

like

a

set

it

and

forget

it
,

which

is

great
,

you

know
,

yeah
.

And

then

everything

else
.

I

try

to

just

keep

really

simple
,

because

once

I

got

that

level

right
,

I

was

able

to

get

rid

of

the

skin

care

stuff

right

for

my

burning

skin

care
,

the

hair

care

stuff
,

the

supplements

for

that

I'm

really

big

on
.

Let's

make

it

more

simple

rather

than

I

feel

like

a

lot

of

these

med

spas

or

scammy

places

or

wellness

coaches
.

They

just

overcomplicate
,

it's

like

they

just

throw

more

at

you
.

We

got

to

owe

you

this
.

We

got

to

fix

this
.

We

got

to

throw

it

at

this

and

this

and

this
.

Speaker 1
5:31

Right
,

and

I

do

think

there's

a

reason

why

you

don't

want

to

overdo

it

because

they're

still

reacting

in

your

body
.

They're

still

doing

something
,

otherwise

they

wouldn't

be

telling

you

to

take

something
,

so

the

reaction

is

still

very

much

there
.

So

I'm

a

person

that

is
,

I

don't

do

supplements
,

and

I

know

some

people

will

like

roll

their

eyes

at

me
,

oh

my

gosh
.

But

here's

the

thing

I

don't

have

good

kidneys
.

First

of

all
,

I

can't

process

all

that

extra
.

Speaker 1
5:53

You

know

and

I

think

that

we

have

to

take

that

in

consideration

how

is

our

body

processing

all

of

this
?

It's

not

a

harmless

supplement
.

When

you're

doing

that
,

it's

not

a

harmless

whatever
.

Do

it

with

intention
.

But

also
,

when

you

go

to

get

hormones

or

look

at

your

hormone

replacement

therapies
,

make

sure

that

you

provide

information

to

your

provider

that

you're

on

these

supplements
,

because

they

can

react

negatively

if

you

are

taking

something

that

maybe

would

react

to

that
,

even

skincare

products

can
.

Speaker 2
6:25

So

if

you're

not
,

maybe

you

bought

something

that

is

like

I

don't

know
.

I

know

people

will

buy

things

that

are

like

cellulite

reduction

creams

or

whatever
.

Right
,

so

even

something

that

simple
,

because

testosterone

relies

on

oil

to

get

into

the

bloodstream

through

the

skin
.

If

you're

putting

something

on

your

skin

that

could

be

creating

an

additional

barrier
,

you're

going

to

be

wasting

money
.

You're

not

getting

all

of

that

cream

Isn't

getting

absorbed

into

creating

testosterone

in

your

body
,

right
?

So

it's

just

so

many

small

variables

that

people

don't

consider
.

Speaker 2
6:56

They'll

be

like

well
,

this

isn't

working
,

or

I'm

having

this

reaction
,

and

I

meet

people

all

the

time

who

haven't

just

taken

a

step

back

and

looked

at

all

of

the

details

of

what

they're

taking
.

People

don't

get

their

supplements
.

They

dislike

the

consider

part

of

their

diet

rather

than

when

someone's

like

can

you

list

off

what

you're

taking
?

And

I

learned

the

hard

way
.

Zinc

actually

can

metabolize

testosterone

faster

and

I

was

taking

a

ton

of

zinc

Interesting
,

so

OK
,

well
,

let's

not

do

that
.

I

also

learned

that

zinc

can

lead

to

anemia
,

and

that's

another

thing
.

There's

just

so

many

facets

to

this

that

get

really

out

of

control

when

we

just

start

to

take

supplements

and

people

will

say
,

well
,

but

it

was

through

my

coach
,

it

was

through

my

naturopath

and

I'm

like

I

still

always

suggest
,

at

least

at

the

very

least
,

talk

with

a

pharmacist
,

because

they're

going

to

know

a

lot

more
.

Speaker 2
7:48

They'll

know

more

than

your

doctor
.

They'll

know

more

than

that

holistic

coach
.

If

you

get

prescribed

something
,

just

say

hey
,

because

they'll

ask

when

you

go

pick

up

a

drug
,

do

you

want

to

do

a

consult

with

a

pharmacist
?

You

could

say

yeah

and

be

like

I'm

taking

these
.

Do

you

know

of

any

interactions

or

resources

where

I

can

look

into

this

some

more
?

And

it's

really

important

because

a

lot

of

people

end

up

having

they'll

be

like
,

oh
,

I'm

having

this

new

symptom
,

or

they'll

think

it's

something

unrelated
,

and

it

really

just

boils

down

to

they

have

two

things

that

are

interacting
.

Speaker 1
8:16

Right
,

and

I

feel

like

that's

something

that

we

have

to

be

aware

of

all

the

time
.

When

any

medication
,

any

supplement
,

you

have

to

know

what

you're

putting

in

your

body

and

how

it's

going

to

respond

and

play

nice

with

other

things

that

you're

putting

in

your

body
.

And

there's

something

that

I

think

that

we

do

need

to

be

aware

of

as

well
.

So
,

because

I've

had

an

ophrectomy

bilaterally
,

which

means

both

ovaries

are

gone
,

I

cannot

produce

more

of

something

that

I'm

not

producing

at

all
.

So

I

know

a

lot

of

people

will

say
,

take

this

supplement

or

try

natural

yams

and

that's

going

to

increase

your

testosterone
.

I

don't

have

a

hormone

factory
,

I

don't

got

it
,

so

I

can't

produce

something

more

if

I

am

not

producing

it
.

Speaker 2
8:59

Right
,

you

have

to

have

those

building

blocks
,

and

there

is

some

to

be

said
,

for

there

are

tissues

throughout

the

body

that

have

the

capacity

for

synthesizing

the

hormones
,

but

they

typically

act

locally

or

they're

not

enough

to

raise

the

blood

levels
.

So
,

yes
,

testosterone

is

made

in

other

parts

of

the

body
.

Clearly

for

me
,

in

a

lot

of

us

we

still

need

to

supplement

with

it
.

Right
,

right
,

estrogen

can

be

made

in

a

lot

of

tissues
.

That

doesn't

mean

that

your

adipose

tissue
,

which

is

fat
,

is

going

to

be

able

to

make

enough

estrogen

to

make

your

hot

flashes

go

away
.

Right
,

because

with

fat

it's

funny

to

me
,

because

with

fat

mentality

it's

like
,

ok
,

well
,

just

get

fat
,

because

fat

makes

a

lot

of

estrogen
.

So

I

guess

a

natural

way

to

increase

your

estrogen

levels

is

to

get

really
,

really

fat
.

Speaker 2
9:45

Just

increase

that

adipose

tissue

and

yeah

it'll

be

great
.

Speaker 2
9:49

It'll

be

great
,

whatever

you

want

to

do
.

So

I

mean
,

I

just

think

that's

how

my

brain

gets

when

it

comes

to

this

stuff
.

I

look

at

the

biochemistry

of

it
,

and

that's

why

testosterone

is

really

interesting

in

that

way
,

because

it's

only

made

in

a

specific

part

of

the

ovary

and

it

has

a

completely

different

method

of

interacting

in

the

body

than

estrogen

does
.

Right
,

and

so

that's

another

thing

to

keep

in

mind
.

Right
,

it's

not

OK
.

Testosterone

and

estrogen

are

made

in

the

ovaries
.

Well
,

they

are
,

but

they're

made

in

different

cells

and

they're

made

in

different

ways
.

And

everyone

knows

I

feel

like

a

lot

of

people

know

testosterone

can

convert

into

estrogen
.

Speaker 2
10:24

Yes
,

and

so

that's

another

thing
,

people

are

like

oh
,

we

got

to

be

careful

because

your

estrogen

levels

arise
.

I

will

tell

you

that

in

the

four

years

we've

been

tracking

my

hormone

levels

as

long

as

my

dosing

is

right

with

my

pellet

I've

never

once

had

elevated

estrogen

levels
.

And

I

know

estrogen

fluctuates

significantly

so

it

can

be

really

hard

to

determine

what

is

even

a

normal

estrogen

level
.

But

we've

tracked

mine

so

closely

for

four

years

that

we

know

where

I'm

at
.

The

only

time

my

estrogen

is

ever

spiked

is

when

my

testosterone

plummets
.

Speaker 2
10:55

It's

like
,

oh

my

god
,

it's

like

my

ovary

is

over-correcting
.

It's

very

bizarre
.

And

then

my

ovary

hurts
.

When

my

testosterone

levels

are

higher
,

my

estrogen

levels

are

super

chill

and

my

ovary

never

hurts

and

it's

like

calm

down
.

But

those

reactions

do

happen
,

right

Like

there

is

a

constant

flow

with

how

the

body

is

making

hormones

and

it

can

do

backward

reactions

and

it

can

do

forward

reactions
.

And

we've

got

three

types

of

estrogen

right
,

when

you

take

hormone

replacement

therapy
,

you're

only

on

one

of

those

types
,

but

that's

OK

because

we

do

make

the

other

types

of

estrogen

as

well
.

Speaker 1
11:32

Interesting
.

See
,

these

are

things

that

we

need

to

talk

more

about

because

it's

not

Simple
,

but

I

think

the

more

we

understand

it
,

the

better

we

can

advocate

for

our

care
.

Speaker 2
11:46

Yes
,

and

I

even

speak

with

a

this

is

brilliant

woman

that

speaks

with

me
.

She's

a

molecular

biologist

PhD
.

Her

and

I

get

into

this
.

Her

and

I

both

go

through

literature
.

We're

like
,

okay
,

so

let's

look

at

this

type

of

estrogen

and

like

someone

will

be

like
,

well
,

I

don't

have

any

free

testosterone

or

total

testosterone
,

but

I'm

having

all

these

high

testosterone

symptoms

and

it's

like
,

well
,

there's

actually

a

pathway

where

a

progesterone

can

turn

into

something

called

DHT
,

which

is

stronger

than

testosterone
.

It's

just

like

the

biochemical

pathways
,

and

that's

my

education

is

in

biochemistry
,

right
,

so

I'm

always

looking

at

these

pathways

and

how

can

they

be

happening
?

Hormone Balancing and Risks in Therapy

Speaker 2
12:27

And

the

body

the

first

thing

we

learn

in

biochemistry

is

that

the

body

is

a

survival

machine

and

it

will

find

a

way
.

So

it

will

create
,

however
,

the

pathways

it

needs

to

create

to

get

to

what

it

wants

as

it's

in

goal
.

Sometimes

that

doesn't

mean

good

for

us
.

Sometimes

that

just

means

survival

for

the

body
.

So

you

get

into

these

situations

where

it's

like
,

okay
,

you're

not

having

enough

testosterone
,

but

it's

making

DHT
.

But

that's

not

good

because

that

causes

a

lot

of

those

like

the

PCOS

type

of

care

growth

and

whatnot
.

Speaker 2
12:56

So

and

I

think

that's

what

people

intend

when

they

say

hormone

balancing
.

I

think

that's

what

they

mean
,

because

they'll

say

we'll

have

one

camp

that's

like

you

gotta

balance

your

hormones
,

so

the

other

camp

that's

like

you

can't

balance

hormones

because

they're

always

fluctuating
.

But

I

think

the

middle

ground

is

hey
,

how

do

we

give

your

body

the

right

building

blocks

so

the

body

can

do

its

natural

balancing

act
?

We're

not

gonna

be

able

to

do

it
.

We're

not

gonna

be

able

to

tell

it

what

to

do
.

Necessarily

which

is

another

thing

I

laugh

about

when

people

are

like

let's

detox

your

estrogen

through

your

liver

and

it's

gotta

go

this

pathway
,

I'm

like

you

are

never

going

to

be

able

to

control

it

that

way
.

That

would

be

like

the

most

precise

medicine

that

we're

not

there

yet

with
.

Speaker 2
13:42

We

can

just

give

it

what

it

needs

to

hopefully

promote

it

to

go

the

right

way
.

And

so

that's

really

important

with

what's

happening

when

we're

giving

it

these

building

blocks
.

And
,

like

you

were

saying
,

if

you

don't

have

the

building

blocks

they're

not

gonna

happen

anyway
.

So

sometimes

you

just

gotta

get

it
,

however

you

can
,

and

then

go

from

there
.

Speaker 1
14:03

I

like

to

think

of

it
.

I

was

talking

to

a

friend

of

mine

the

other

day

about

this

with

you

know
,

balance

is

very

ambiguous

when

we're

talking

hormones
,

right
?

So

I

like

to

think

of

like

the

lines

of

like

the

different

hormones

in

between

a

bracket
.

Where

is

your

balance
?

Like
,

where

are

you

gonna

thrive

the

most

and

feel

the

best
?

If

one

is

way

over

here

and

the

other

is

over

here
,

you're

not
.

There's

no

middle

ground
.

You're

gonna

feel

awful

either

way
.

But

if

you

have

those

markers

of

what

is

your

balance

and

where

you

thrive

and

where

your

body

is

not

in

survival

mode

anymore
,

that's

your

balance
,

as

long

as

it's

not

swinging

one

direction

or

another

to

create

long-term

bad

effects
.

Speaker 2
14:49

It

should

be

long-term

and

that's
.

You

know
,

in

defense

of

a

lot

of

the

you

know

what

you

would

call

like

more

like

traditional

doctors
.

In

their

defense
,

they're

right

when

they

say

there's

just

no

good

way

to

know
.

Right
,

there

is

a

good

way

to

know
,

but

it

requires

a

lot

of

time

and

effort
.

For

me
,

with

the

amount

of

data

I

have

on

my

body

over

four

years
,

I

understand

like

that

is

a

massive

privilege
,

but

I

do

my

best

to

utilize

that

as

like

an

example
.

Right
,

right

Doctor

can

say
,

well
,

you'll

never

know

your

estrogen

levels
.

It

varies

too

much
.

You'll

never

know

this

and

I'm

gonna

know

that

we

just

can't

get

it

with

one

snapshot
.

They're

right
,

you

can't
.

Speaker 2
15:20

But

if

you

find

the

right

provider

and

I

always

think

one

of

the

green

flags

defining

a

good

provider

is

them

wanting

to

be

your

partner

and

you

know
,

not

just

rolling

over

every

time

you

say
,

well
,

I

want

this
,

but

then

you

know

having

a

collaboration

there
,

like
,

hey
,

I'm

really

curious
.

Do

you

think

we

can

test

this

right

now
,

which

my

provider's

always

done

for

me
,

cause

I've

been
,

like

you

know
,

I

feel

really

off
.

I'm

really

curious

to

know

where

am

I

at

like

right

now
.

It

also

helps

that

I

have

access

to

a

lab

that

will

give

me

my

results

within

like

12

hours
,

yeah
,

which

I

know

is

really

unheard

of

in

a

lot

of

places

and

so

sometimes

within

like

eight
.

So

I've

got

this

data

where

I

was

telling

you
,

like

I

can

see
,

you

know

we're

testing
.

Testosterone

plummets

down
,

estrogen

skyrockets
.

Well
,

why

would

that

happen
,

right
?

Everyone's

like

well
,

testosterone

makes

it

turns

into

estrogen
.

Speaker 2
16:03

It's

like
,

well
,

clearly
,

my

body

is

using

what

it

can

you

know
,

and

it's

I

don't

have

a

reserve

and

it's

just

turning

into

estrogen
,

whatever
,

but

it's

being

able

to

collect

that

data
,

to

find

out

where

you

feel

best
.

Bye
,

because

that

data

is

hard

to

collect
.

I

think

that

the

best

providers

and

clinicians

that

I've

met

are

typically

ones

that

say

we're

going

to

just

do

everything

based

on

how

you

feel
.

That

is

good

enough
,

honestly
,

because

someone

may

get

their

test

off
,

surrounded

in

a

way

that

I

think

is

inferior
,

but

then

they

get

lab

work

that

shows

good

and

their

symptoms

are

resolved

and

they

feel

amazing
.

That's
,

honestly
,

what

matters
.

At

the

end

of

the

day
,

the

good

providers

they

will

say

that

we

just

go

based

on

symptoms
,

we

adjust

dose

based

on

symptoms
.

Speaker 2
16:49

As

long

as

the

rest

of

your

health

comes

back

as

fine
,

go

in

for

your

physical

and

nothing

else

is

out

of

line
.

Your

lip

profile

is

good

and

everything's

healthy
.

A

doctor

may

know

a

couple

of

people

who've

provided

has

been

like

your

testosterone

is

too

high
.

It's

not
,

it's

literally

like

90
.

They're

like

well
,

that's

way

too

high
.

They're

like

but

this

I

feel

so

good

and

they're

not

having

side

effects
.

It's

like

why

are

they

enforcing

their

belief

Based
?

Speaker 1
17:14

on

no

data

right
,

there's

no

clinical

data
.

Speaker 2
17:17

It's

based

on

just

this

idea

that

they've

stuck

to
.

It's

frustrating

Really
.

It's

like

we

have

to

find

a

provider

that

is

just

willing

to

work

in

a

collaborative

nature

and

willing

to

go

based

on

how

we

feel
.

Speaker 1
17:33

What

are

some

of

the

things

that

we

should

be

aware

of
?

In

doing

hormone

replacement

therapies
?

Are

there

risks

involved

that

we

need

to

be

looking

at

now
,

but

even

long

term
.

Speaker 2
17:43

I

think

when

it

comes

to

the

long

term

data
,

what

we

have

currently

is

based

on

that

women's

health

initiative
,

which

is

incredibly

flawed
.

Everyone

knows

it's

flawed
.

At

least

now

it's

publicly

known

and

everyone's

like

okay
,

ignore

it
,

because

it

was

based

on

conjugated

estrogens

that

we

don't

even

use

anymore
.

Well
,

I

guess

some

people

out

there

may

still

use

permarin
,

but

the

long

term

data

is

slowly

coming

out

better

on

that
.

I

think

it's

safe

to

say

that

going

off

clinical

guidelines

for

estrogen

use

is

pretty

solid

at

this

point
.

You

can

go

to

the

North

American

Menopause

Society

and

see

a

consensus

statement

from

them
.

I

would

say
,

for

the

most

part
,

staying

away

from

anything

too

fringe

I

say

that

a

lot

but

anything

that's

too

radical
.

Maybe

try

to

find

the

middle

ground

on

that
,

because

I

know

again

there's

a

lot

of

fear

mongering

with

estrogen

replacement

therapy
.

But

let's

look

at

the

other

side

of

that

coin

as

well

the

dangers

of

losing

estrogen
.

I

think

it

should

resound

even

more

in

the

endometriosis

community
.

Just

because

we

know

what

happens

when

we're

put

on

or

ELISA

or

Lupron
,

we

know

firsthand

what

happens

when

we

deplete

the

estrogen
.

I

think

we

know

what

happens

long

term
.

I

think

that

when

it

comes

to

estrogen
.

It's

a

lot

easier

now

to

find

that

data
.

When

it

comes

to

what

to

look

for

with

testosterone
,

that's

a

lot

harder
,

right
.

Speaker 2
19:08

I

feel

like

the

best

way

to

navigate

that

is
,

honestly
,

just

if

you're

accessing

a

pellet
,

make

sure

that

it's

not

super

expensive
.

I

will

say

I

think

mine

breaks

down

to

$25

a

week
.

That's

so

bad
?

No
,

it's

not
.

That

includes

the

visit
.

The

doctor

is

not

covered

in

network
,

so

my

office

visit

is

$60
.

Then

the

pellet

itself

may

be

like

$180
,

$200
.

It

can

go

up

depending

on

how

much

more

milligram

I

get

put

in
.

Then

you

can

extend

it

between

12

and

14

weeks
.

But

when

I've

met

people

who

will

go

and

they'll

say

like

$500

for

a

console

and

then

$500

every

visit
,

and

I'm

like
,

okay
,

that

is

just

a

rip-off
,

at

that

point

I'm

like

just

go

to

somebody

and

get

a

cream
,

right
,

if

that's

more

valuable
.

Speaker 2
19:56

At

that

point

it's

like

no
,

no
,

that's

a

rip-off
.

I'm

always

like
,

first

and

foremost
,

let's

look

at

this

financially
,

right
.

I

don't

think

anybody

should

be

spending

that

kind

of

money

for

it
,

because

I

know

at

that

point

you

can

just

get

it

another

way
.

I

think

when

you're

looking

for

when

it

comes

to

the

testosterone
.

That's

probably

the

biggest

thing
,

honestly

is

the

cost
,

then

your

dosing
.

You

just

want

to

make

sure

that

whoever

is

doing

it

actually

cares

about

monitoring
.

I'll

meet

people

who

are

like

well
,

I

got

my

testosterone

pellet

and

then

they're

not

even

going

to

check

me

for

six

weeks
.

That's

a

red

flag
.

Insurance

should

cover

blood

work
.

Insurance

does

no

problem
,

even

though

they're

not
.

My

provider

is

not

covered
.

Insurance

covers

the

blood

work

part
.

If

you're

getting

a

cream
,

make

sure

that

your

doctor

can

at

least

tell

you

where

it's

compounded

from

what's

in

it
?

Speaker 2
20:43

and

then

also
,

do

they

have

reasoning

behind

the

dose

they

want

you

to

be

on
?

When

are

they

willing

to

test

you

again
?

Are

they

willing

to

change

the

prescription

based

on

how

you're

feeling
?

Sometimes
,

because

testosterone

gets

metabolized

so

quickly
,

sometimes

patients

need

to

apply

it

twice

a

day
,

right
,

so

every

12

hours
,

because

some

providers

will

butt

heads

on

that

and

be

like
,

no
,

we're

not

going

to

do

that
.

I

mean

that's

just

absurd
,

honestly
,

because

that's

that

doesn't

really

matter
.

It

should

be

based

on

the

patient
,

not

their

belief

system
,

but

it'd

be

a

red

flag

For

me
.

That's

a

red

flag
.

Speaker 2
21:21

They

need

to

be

at

least

monitoring

your

symptoms
.

How

are

you

feeling

If

we

do

it

this

way
?

Does

it

make

you

feel

better
?

And

that's

the

same

way

for

my

prescription

drugs
,

right
,

right
,

like
.

I

have

one

that's

broken

up

kind

of

weird
.

My

doctor

the

first

time

he

saw

that

he's

like

that

is

a

weird

dosing

schedule
,

but

it

doesn't

matter

because

that's

what

works
.

It's

worked
.

And

the

progesterone

progesterone

I'm

actually

more

concerned

about

because

when

it

gets

dispensed

through

a

med

spot

or

a

wellness

coach

or

something
,

just

because

that

seems

to

be

made

more

on

the

black

market

than

anything

else

Interesting

yeah
.

Speaker 2
21:54

You

just

don't

know

what's

in

that
.

I

mean

you

can

find

a

progesterone

cream

anywhere
.

Speaker 1
21:59

It's

just

like

sold

everywhere
.

Speaker 2
22:00

It's

wild
,

and

so

I

trust

that

even

less
.

And

then
,

of

course
,

there

is

a
.

I'll

have

to

send

this

to

you
.

There's

an

amazing

publication

on

estrogen

dosing

and

route

of

administration

and

which

type

of

estrogen
,

and

it

is

so

phenomenal

they

do

different

types

of

vaginal

estrogen

insert

and

how

much

the

blood

levels

actually

increase

in

estrogen

Cause

there's

always

that

argument

does

vaginal

estrogen

actually

increase

your

serum

levels

or

not
?

And

it

is

based

on

dosing

and

even

where

you

place

it
,

when

you

put

it

in

Interesting
.

Speaker 2
22:35

Yeah
,

it's

really
,

really

interesting
.

And

then
,

of

course
,

the

different

types
.

You

know
,

the

patch
,

the

oral
.

They

even

use

the

old

school

primary

in

it

and

it's

it's

a

really

great

publication
.

It's

really

technical
,

yeah
,

but

it's

also

just

invaluable

data

that

everybody

should

have

who's

taking

estrogen

of

any

kind
,

cause

it

goes

into

risks
,

benefits
,

how

fast

the

levels

rise

in

the

blood

after

taking

it
,

and

it's

really

really

great
,

and

so

I'm

hoping

in

the

future

we

can

have

something

like

that

for

testosterone

Hormone Replacement Therapy Considerations and Controversies

Speaker 2
23:06

right
.

Speaker 2
23:06

Because

you

know

the

different

ways

that

you

can

get

it
,

safety

profiles
,

and

I

will

say

a

friend

of

mine

really

wanted

to

do

the

pellets

but
,

as

with

case

with

a

lot

of

endometriosis

patients
,

she

has

this

a

bizarre
,

bizarre

comorbidities

and

one

of

them

is

her

scarring
.

Yeah
,

she's

really

bad
,

and

so

her

body

wouldn't

actually

accept

the

pellet
.

It

just

kept

spitting

it

out

Like

and

she

would

just

scar

horribly
.

So

it

wasn't

a

fit

for

her
.

Speaker 2
23:32

And

that

kind

of

was

like

a
.

That

was

one

of

those

things

where

I

was

like
,

oh
,

I

hadn't

even

considered

that

before

as

a

possibility
.

Speaker 1
23:37

Yeah
.

Speaker 2
23:37

So

for

her

it

didn't

work
,

and

I

know

that

I've
.

Actually
,

I

was

getting

a

hundred

milligrams

and

I

learned

that

I

couldn't

get

a

whole

100

milligrams
.

And

this

is

the

other

issue

with

some

of

the

med

spas

they

don't

have

the

ability

to

like

do

more

precise

dosing

with

the

pellets
.

Right
,

I

got

a

hundred

milligrams

pudding
,

so

it

was

easy
.

Well
,

my

body

kicked

it

out

pretty

easily
.

Speaker 1
23:59

Like
.

Speaker 2
23:59

I

was

riding

and

I

was

probably

more

active

than

I

should

have

been
,

but

it

came

out

and

my

doctor

was

mortified
.

He's

like

you're

ruining

my

like
.

Patients

never

have

a

pellet

come

out
.

But

what

we

ended

up

doing

was

breaking

it

into

two

fifties

so

50

milligram
,

50

milligram

and

placing

them

differently

inside
.

Speaker 2
24:19

It's

like

so

that's

one

of

those

things

where

it's

like
,

okay
,

based

on

your

level

of

activity

body
,

yeah

Right
,

you

go

to

a

bio

team

head

spot

and

they're

just

going

to
,

not
,

they're

just

gonna

put

it

in

out

the

door
,

yeah
.

Speaker 1
24:34

I

think

that's

well
,

and

that's

part

of

it

too

is

like

knowing

who's

putting

it

in
,

how

they

are

gonna

cater

to

your

body

and

to

your

needs

and

your

lifestyle
,

because

not

everyone

is

gonna

react

the

same

to

everything
,

and

that's

why

I

think

it's

so

individualized
.

But

the

thing

about

estrogen
,

too
,

that

more

research

is

starting

to

back

up

is
,

if

you

go

into

early

menopause

and

or

surgical

menopause
,

your

risk

of

dementia

is

much

greater

without

that

estrogen

replacement
,

and

I

think

that

it's

a

fairly

new

thing

that's

starting

to

come

out

more

and

more

like

no
,

this

is

not

just

about

dry
,

that's

not

just

about

your

skin

getting

loose

although

that

is

for

some

of

us

a

hard

thing

but

it

is

about

the

memory
.

What

is

your

longevity

without

it
?

What

is

your

longevity

with

it
?

Speaker 1
25:29

You

have

to

look

at

the

big

picture
,

but

you

also

have

to

consider

where

you

are

now
.

You've

gotta

feel

better
,

you've

gotta

be

able

to
,

you

know
,

not

just

survive

in

life
,

and

I

think

that's

where

a

lot

of

us

have

been
,

because

we

lack

the

education

to

give

us

informed

consent

and

there's

so

much

coming

out

right

now
.

I

think

a

lot

of

the

people

that

you

probably

listen

to

on

podcasts

or

online

are

probably

similar

to

me
,

and

there's

so

much

that

even

they're

learning

right

now
.

That

has

just

been

like

oh
,

I

never

even

thought

that

it

would

affect

this

system

of

my

body
,

but

clearly

it

is
,

and

how

intertwined

that

is
.

Speaker 2
26:05

It's

frustrating

because

my

doctor

he's

probably

like

he's

in

his

mid-80s

and

he's

been

doing

this

for

so

long
,

for

so

many

decades
.

And

it's

frustrating

because

he'll

just

sit

back

and

he's

like

yeah
,

yeah

yeah
,

yeah
,

you've

known

this
,

but

the

thing

is
,

there's

always

been

such

a

pushback
,

right
?

Speaker 2
26:24

And

even

though

he's

like
,

I'm

an

OBGYN

by

trade
.

Technically
,

you

know
,

he's

like
,

but

I've

never

done

obstetrics

outside

of

school
.

He's

like
,

I've

only

done

gynecology
.

And

it's

sad

that
,

because

of

the

way

the

institutions

work
,

nobody

knows

about

someone

like

him
,

but

it's

colleagues

do

within

the

network
,

right
,

right
,

you

know
,

they

know
,

but

he

you

know
.

And

now

it's

like

if

you're

not

writing

a

book

or

you're

on

social

media

and

no

one's

gonna

know

who

you

are
.

And

unfortunately
,

when

it

comes

to

the

hormone

replacement

therapy

space
,

we

have

two

very

differing

camps

right

now
.

And

it

is

I

don't

know

if

you've

seen

it
,

it's

like

drama

and

I

love

to

watch

it

from

afar
.

You've

got

these

big

time

like

self-reclaimed

menopause

experts
,

new

York

Times

best

sellers
,

and

they

really

think

that

they

are

the

best

ever
,

fighting

with

these

other

ones

that

are

actually

considered

maybe

the

fringe
,

but

they're

the

ones

actually

working

with

patients
,

not

just

screaming

on

the

internet
.

Speaker 1
27:19

Right
.

Speaker 2
27:20

You

know

it's

being

the

difference

that's

happening
,

rather

than

just

standing

by

old

doctrine
.

You

know

the

high

and

mighty
,

the

high

like

we

were

talking

about

before
.

Speaker 2
27:28

Rather
,

you

know

and

these

are

like

the

more

outside

the

box

thinkers

that

are

realizing

the

human

body

is

not

just

cut

and

dry
,

right
,

and

I'm

loving

this

interaction
.

And

then
,

of

course
,

there's

like

Rebecca

Glaser
.

I

was

telling

you

about

her
.

She

just

stays

completely

silent
.

I

wish

I

could

get

her

on

social

media
,

but

that's

just

not

her

jam
.

But

you

know
,

she's

actually

out

there

doing

the

publications

Challenges With Medical Guidelines and Research

Speaker 2
27:50

on

it
.

Speaker 2
27:50

Couple

of

years

ago
,

menopause

organization

from

Australia
,

they

were

rewriting

their

guidelines
.

I

had

emailed

them

because

I

said

I

was

looking

for

your

guidelines

and

you

don't

have

anything

from

Rebecca

in

your

guidelines
.

And

they

responded

and

like
,

well
,

we

don't

like

her

research
.

Essentially

is

what

they

said
.

They

were

like

well
,

you

know
,

it's

not

rigorous

enough
.

And

I

said

but

your

clinical

guidelines

include

quote

expert

opinion

and

that's

not

based

on

any

data
.

I

was

like
,

because

I

know

how

clinical

guidelines

were
.

Speaker 2
28:17

Anyway
,

they

didn't

want

to

talk

about

it
.

They

were

just

like

okay
,

well
,

yeah
,

and

you

mind

handing

out

this

pamphlet

that

we're

doing

in

a

survey

on

I

don't

know

what

it

was

some

sort

of

hormone

replacement

therapy

that

they

were

going

to

be

trialing

for

updating

their

guidelines
.

And

I

looked

through

the

nice

guidelines

in

England

they

only

have

testosterone

listed

for

sex

drive

and

that's

it
,

nothing

else

one

tiny

sentence

and

again

you'll

bring

up

well
,

what

about

like

Rebecca

Glaser's

work
?

And

they're

like
,

oh

well
,

you

know

it's

not

rigorous

enough
,

and

I'm

like

you've

got

to

be

kidding

me
.

It's

the

same

thing

with

in

vitriosis
.

Speaker 2
28:49

You

point

out

these

excision

studies
,

like

not

rigorous

enough
.

I'm

like

half

the

stuff

that

you're

relying

on

is

much

more

flawed
.

And

so

it's

just

frustrating

because

there

is

data

there

but

they

will

come

up

with

whatever

they

can

to

try

to

discount

it
,

and

I

find

that

really

it's

fascinating
.

But

the

people

who

follow

those

camps
,

they

fall

in

line

with

that
.

Right
,

you

know

the

very

doctrine

camp
.

They're

like

well
,

there's

nothing

in

the

guidelines

and

they

just

stop

at

that
.

They

don't

understand

the

complication

behind

you

know
,

developing

the

guidelines
.

But

then

you've

got

the

other

group

that's

like
,

hey
,

the

guidelines

aren't

right
,

we

need

to

update

the

guidelines
.

Speaker 2
29:28

And

so

it's

funny

to

see

the

parallel

there

with

the

in

vitriosis
,

yep
,

and

the

hormone

thing
.

They're

like

that's

the

same

thing
.

Fortunately

we

have

bigger

names

fighting

for

hormone

replacement

therapy

than

we

do

for
.

You

know
,

on

the

endometriosis

side
,

yeah
,

for

both

camps

the

voices

are

kind

of

getting

evened

out
.

But

I'm

enjoying

that
.

I

think

that's

going

to

help

us

move

forward
.

Speaker 2
29:53

Honestly
,

more

Mm-hmm
.

And

I

think

we're

as

you

go

through

it

and

as

we

move

through

it
,

because

I

know

at

the

beginning

of

my

journey

I

was

a

lot

different

than

I

am

now
.

I

was

more

like

hard

line

and

now

working

with

more

patients
.

Every

time

I

work

with

a

new

patient

or

I

chat

with

somebody
,

I'm

humbled

in

some

way
.

Mm-hmm
,

you

know
,

yeah
,

I'm

like
,

oh
,

wow
,

okay
,

that

doesn't

work

for

everybody

Like

I

thought

it

would
,

and

so

I

see

that

with
,

like

these

coaches

that

I

can

tell

they

have

figured

out

some

of

that

worked

for

them

and

they

wanted

to

work

for

everybody
,

and

they're

going

to

apply

it

to

everybody
.

Speaker 2
30:25

I'm

like

no
,

I

used

to

think

that

too
,

and

now

it's

like

we

just

have

to
,

like

you

said
,

get

out

of

the

survival

mode

and

just

find

a

way

to

at

least

improve

quality

of

life
.

That's

what

I

always

say

and

like

let's

improve

quality

of

life

first

and

then

move

from

there
.

And

staying

hard

lined

about

following

a

guideline

based

on

sub-hard

data

just

to

follow

it

but

still

have

feel

miserable
,

that

doesn't

make

sense

to

me
.

Speaker 1
30:50

That's

not

logical
.

Speaker 2
30:53

And

that's

a

poor

provider
,

you

know
.

Speaker 1
30:56

I

also

think

those

that

are

foundationless

in

their

research

we

have

to

be

aware

of
.

On

social

media
,

I

mean
,

this

is

something

that

when

you're

looking

at

following

a

provider

or

getting

advice

from
,

it's

important

to

look

at

where

is

the

research

coming

from
?

If

they're

making

big
,

bold

claims

of

something
,

yeah
,

because

and

this

includes

endometriosis

but

hormone

replacement

therapies

you

need

to

know
,

just

like

you

said
,

where

it's

compounded
,

what

it's

compounded

with
.

If

they're

trying

to

sell

you

something
,

a

program
,

for

thousands

of

dollars
,

chances

are

it's

not

got

a

good

foundation
.

Speaker 2
31:36

Yeah
,

and
,

like

I

point

this

out

to

people
,

yes
,

I'm

lucky

to

have

found

my

provider

and

to

be

able

to

get

to

him
.

I

would

hands

down

argue

he

is

one

of

the

best

in

the

world

when

it

comes

to

hormone

replacement

therapy
.

And

I

pay

$25

a

week
,

right
,

right
,

I'm

not

paying

something

that's

completely

unattainable
.

My

ADHD
,

like

the

vibrance
,

is

more

expensive

every

month
.

Yeah
,

if

I

didn't

have

insurance

then

this

would

be
.

You

know

what

I

mean
,

right
?

That's

why

I'm

like

it

should

be

within

the

realm

of

possibility
.

So

that's

why

the

pricing

thing

I

look

at

and

I'm

just

like
,

don't

get

conned
.

Speaker 1
32:09

You

know
,

and

it's

so

easy

when

we're

desperate
.

Speaker 2
32:11

We

want

everything

to

work
.

I

almost

did

too
,

because

I

was

looking

at

different

hormone

providers

and

I

found

this

one
.

It

was

like
,

oh
,

this

looks

like

a

really

great

one
.

And

then

it

was

like

a

$500

consult

oh

my

God
,

what
.

That

just

kind

of

blew

my

mind
.

So

it's

definitely
,

it's

just

important

to

maintain
,

you

know
,

like

a

middle

ground

of

some

kind
,

right
,

try

to

find
.

Speaker 2
32:30

I

always

say

the

truth

is

somewhere

in

the

middle

of

the

extremes
,

and

then

where

your

truth

lies

is

going

to

be

somewhere

on

a

spectrum
,

and

then

where

you

feel

best

is

also

going

to

be

on

a

spectrum
.

Speaker 2
32:41

And

it's

good

for

me

to

remember

that

when

I'm

working

and

chatting

with

other

people
,

basically

what

I

have

to

remind

myself

is
,

instead

of

being

like
,

okay
,

is

this

person

doing

what

I

want

them

to

do

or

what

I

think

they

should

do
,

I

have

to

stop

and

ask

how

do

you

feel

right

now
?

You

know

like
,

what

do

you

think

could

improve
?

And

you

know
,

if

I'm

working

with

someone

as

a

patient

advocate
,

you

know

we

sit

down

and

we

look

at

you

know

what

have

they

tried
?

What

kind

of

providers

are

they

seeing
?

Right
,

or

it's

like

somewhere

in

there

there's

always

a

well
,

I'm

following

this

person

on

Instagram
,

or

well
,

I'm

like

this

is

where

we're

going

to

go

wrong

and

it's

always

like

they've

thrown

in

some

weird

supplement

or

they've

are

hard-lined

with

this

one

doctor

that

says

you

have

to

follow

every

guideline

and

they

haven't

opened

up

their

mind

to

maybe

trying

something

else
.

Speaker 2
33:26

It

is

just

very

nuanced

and

I

hope

that
,

as

the

information

continues

to

come

out
,

it

doesn't

get

always

into

the

wrong

hands

Right
,

because

that

happens

too
,

and
,

again
,

anybody
.

Navigating Research and Hormone Replacement Therapy

Speaker 2
33:40

You

just

have

to

be

so

careful

with

the

way

information

is

interpreted

as

well
.

Yes
,

because

you

know

there's

one

really

outspoken

menopause

expert

that

will

take

things

and

write

on

their

blog

about

it

as

an

expert
,

and

I've

read

through

their

analysis

of

some

of

this

information

and

it's

not

good

Interesting
.

I'm

like

she's

actually

interpreting

data

in

a

very

skewed

way
.

She's

very

emotional

and

so

I

think

she

interprets

it

emotionally

as

well
.

Yeah
,

and

I

like

to

take

a

step

back

and

look

at

the

data
.

The

reason

that

a

lot

of

stuff

can

get

published

now

is

because

a

lot

of

it

is

pay

to

play
.

Speaker 1
34:18

Right
.

Speaker 2
34:19

And

so

in

a

lot

of

these

publications
,

when

you're

looking

at

them
,

if

you

just

read

their

analysis

without

digging

into

it

yourself

and

saying

that's

what

you're

interpreting
,

you'll

get

this

very

biased

approach
.

For

instance
,

I

wasn't

sure

I

agreed

with

one

of

her

analysis
,

so

I

looked

at

the

publication

she

was

citing

and

I

looked

at

the

actual

numbers
,

which

is

normally

you

have

to

like

download

in

a

different

accessory

file

or

something

right
,

it's

not

just

always

in

the

paper
,

right
?

And

I

was

actually

looking

at

the

numbers

and

I

was

like
,

no
,

no
,

this

isn't

actually

what

that

was

showing
,

because

they

can

say

statistically

significant
,

but

that

doesn't

mean

anything

meaningful
,

right
,

and

they

love

to

throw

that

in

there
.

Well
,

there

was

a

statistically

significant

and

I'm

like
,

oh

my

God
.

Speaker 1
35:02

One

way

or

the

other
.

Speaker 2
35:03

Was

it

clinically

meaningful
?

Did

it

even

matter
,

right
?

So
,

anyway
,

that's

a

whole

other

thing

when

it

comes

to

research
,

but

if

somebody

is

presenting

research

like

that
,

it's

important

to

be

like

well
,

did

you
?

Speaker 1
35:13

look

at

the

data
.

You

know
,

Did

we

look

at

the

data
?

Good

at

that
.

Is

that

something

that

we

could

say
?

Hey
,

Kate
,

I

came

across

this

research
.

Do

you

mind

looking

at

it

and

seeing

if

this

is

valid
?

Because

I

feel

like

for

a

lot

of

us
.

We

see

this

research

and

we're

very

confused

by

okay
,

is

this

valid
,

is

this

not
?

And

sometimes
,

what

they

state

we

don't

have

access

to
,

which

is
,

I

think
,

absurd
,

because

it's

like

medical

journals

and

things

like

that
.

Speaker 1
35:41

So

if

it's

something

like

that
,

it

is

always

better

to

ask

someone

that

can

analyze

that

data

that

is
,

a

third

party
,

not

someone

who

is

connected

to

that

research

or

that

paper
,

because

it

is

going

to

be

biased

one

way

or

another
.

And

so

finding

someone

that

can

analyze

that

data
,

making

sure

that

it's

accurate
,

give

you

an

accurate

description

of

what

they're

actually

saying

in

that

data
,

is

gonna

benefit

you

in

making

your

next

steps

or
,

and

maybe

help

in

your

opinion

one

way

or

another
.

Speaker 2
36:15

Yeah
,

that's

one

of

my
.

That's

actually

one

of

the

formal

like

roles

of

a

patient

advocate

can

be
,

you

know
,

obtaining

data

like

that

and

looking

at

through

with

the

patient
.

And

when

it

comes

down

to
,

you

know
,

looking

at

data
,

I

have

my

own

network
.

Sometimes

there's

data

that

I'm

there's

some

types

of

statistical

analysis

that

I'm

really

awful

at
,

so

I

have

my

own

resource

group
.

You

know
,

I

have

friends

that

I

can

reach

out

to

and

they'll
,

you

know
,

like
,

oh
,

yeah
,

no
,

this

is

what

that

means

or

doesn't

mean
.

And
,

like

you

know
,

like

gut

check

with

others
,

and

so

I

have

no

problem

when

people

you

know

send

me

something
,

or

like
,

kate
,

you

know
,

what

do

you

think

about
?

Speaker 1
36:46

this
,

and

I

always

have

an

initial

reaction

right
.

Speaker 2
36:48

I'm

always

like

oh

yeah
,

this

is

gonna

be

horrible
.

Speaker 1
36:50

And

then

sometimes

I'm

wrong
.

Somebody

sent

me

one

yesterday
.

Speaker 2
36:52

They're

like
,

hey
,

I'm

thinking

about

buying

this
.

It

was

not

related

to

endometriosis
.

What

do

you

think

it

had

to

do

with

water
?

Oh

yeah
.

And

I

was

like
,

oh

yeah
,

this

is

totally

a

trash

product
.

They're

just

trying

to

make

money
.

So

I

dug

into

it

for

quite

a

while
,

looking

at

research
,

and

went

oh

well
,

actually

there

is

some
.

There's

like

there

actually

is

some

evidence

here

that

it

can

do

X
,

Y

and

Z
.

Here's

the

literature

on

that
.

Don't

know

if

it

can

do

what

it's

claiming

health-wise

Right
.

But

I

had

to

realize

that

my

initial

reaction

to

it

was

not

accurate
.

Speaker 2
37:24

There

actually

is

some

research

done

and

evidence

that

it

did

something

right
.

We

just

don't

know

if

it

did

exactly

what

it

was

claiming
.

So

that's

another

part

of

it
.

But

yeah
,

when

it

comes

to

the

research

part
,

the

gut

check

part

digging

in

with

somebody

else
,

it's

really

important

because

I

will

see

a

lot

of

these
,

like

health

coaches
,

say

that

they're

looking

at

the

data

and

they'll

give

their

analysis
,

and

I

can't

tell

you

how

many

times

it's

been

wrong
.

Speaker 2
37:50

There

are

some

wonderful

well-meaning

ones

on

social

media

that

I've

direct

message

and

said
,

hey
,

actually

this

is

what

I

looked

at

and

this

is

the

result

I

got

from

the

data

and

they've

actually

taken

it

down

or

modified
,

and

that

I

really

appreciated

that

because

I

would

have

no

problem

with

a

peer

doing

that

to

me

either
.

Right
,

kate
,

you

actually

looked

at

this

data

wrong
.

Okay
,

great
.

That's

why

we

have

the

review

process
.

But

unfortunately

now

with

publications

they're

mostly

paid-to-play

and

this

is

why

we

have

retractions
.

I

try

to

tell

people

articles

get

retracted
.

There

was

one

recently

I

reached

out

to

the

editor

about

and

he

thanked

me

because

they

had

approved

a

publication

that

was

citing

a

retracted

article

and

that

can

happen

depending

on

the

dates
.

So

I

double-checked

the

dates

the

article

had

already

been

retracted

by

the

time

they

published

or

had

even

started

writing
,

because

it

had

been

like

six

years

and

I

caught

that
,

like

you
,

can't

cite

a

retracted

publication
.

Speaker 1
38:51

Interesting

Things
,

that

if

you're

not

looking

for

that

stuff

or

you're

not

aware

of

it
,

something

that

you

would

completely

miss
.

And

not

everyone

has

that

skill

set
,

and

that's

why

I

think

it's

important

to

know

like

different

people

that

do

have

that

skill

set
,

so

that

you

get

better

information
.

Speaker 2
39:06

Yeah
,

and

there's

all
.

You

know
.

I

have

my

list

of

resources
.

I

tell

people

I'm

like

like

who

should

I

follow

for

this
?

I'm

like
,

go

here
,

go

there
.

You

know
,

these

people

I

trust
.

Of

course

don't

take

it

as

like

gospel
,

but

you

know

it's

a

start
,

you

know
.

And

then

I'm

always

like

do

your

due

diligence
.

At

the

end

of

the

day
,

that's
.

Speaker 1
39:22

And

what

you

have

to

do
.

That's

for

everything
.

Speaker 2
39:24

That's

for

your

providers
,

that's

for

medications
,

that's

for

supplements
,

everything

that

you're

going

to

take
.

But

I

feel

like
,

when

it

comes

to

hormones
,

when

you're

having

surgery

for

whatever

reason
,

maybe

you

need

to

have

the

ovaries

out
,

maybe

you

just

need

to

hysterectomy
,

but

I

think

it's

important

to

know

that

all

of

that

can

impact

how

your

ovaries

function

long

term
.

And

then
,

just

because

you

left

your

ovaries

doesn't

mean

you

can't

be

having

some

sort

of

issue

that

would

necessitate

hormone

replacement

therapy
.

So

it's

totally

OK

to

find

a

provider

that

will

work

with

you

in

that
,

because

people

will

often

say

I'm

not

going

to

be

like
,

well
,

I'm

not

in

full-blown

menopause

and

I

send

them

to

somebody

that's

called

a

menopause

expert
.

They're

like

does

this

make

sense
?

And

it

does
,

still

should

see

somebody
.

That's

just

their

focus
.

And

so

your

primary

care

physician

may

say

well
,

you're

fine
,

you

still

have

your

ovaries
.

It's

OK

to

pursue

that

further
.

I

think

it's

important

for

people

to

know
,

and

I

think

it's

important

even

if

you

have

both

ovaries
,

one

ovary
,

no

ovaries
.

Speaker 2
40:23

You

can

go

through

any

variety

of

these

fluctuations
.

It

is

so

nuanced

and

customized

for

each

individual

so

it's

hard

to

find

a

provider

that

can

treat

all

of

these

things
.

But

I

think

it's

important

to

note

that

our

OBGYNs

general

OBGYNs

just

like

they

aren't

cut

out

for

endometriosis

surgery
,

they're

not

cut

out

for

proper

hormone

replacement

therapy
.

And
,

as

wonderful

as

our

surgeons

are
,

they're

also

not

hormone

experts
.

So

a

lot

of

people

will

be

like

well
,

I

went

to

so-and-so

and

I'm

like

yes
,

he's

an

exceptional

surgeon
,

really

wonderful
.

Great

that

they

put

you

on

an

estrogen

patch

after

removing

both

ovaries
.

But

it

doesn't

stop

there
.

Unfortunately
,

they're

not

going

to

be

the

expert

in

that
.

So

that

journey

continues

on

and

a

lot

of

people

get

frustrated
.

They're

like

I

thought

I

went

to

an

expert
.

I'm

like

you

did

for

Indo
.

Speaker 1
41:09

But

not

a

hormone

replacement
.

This

is

a

whole

nother

beast
.

Speaker 2
41:12

This

is

a

whole

nother

thing

that

we

did
.

So

I

try

to
.

You

know

it's

important
.

We

need

to

start

working

on

that

beforehand
.

Ideally
,

these

surgeons

would

have

someone

they

could

refer

patients

to
.

But

again
,

who

are

they

going

to

refer

them

to

when

it's

so

difficult
,

right
?

So

I

think

that's

the

trajectory

for

a

lot

of

us
.

I

think

that

it's

just

important

to

track

those

symptoms
,

Even

not

in

full

blown

menopause
,

still

track

the

other

symptoms

that

could

be

hormonally

related
,

and

then

do

your

best

to

find

a

provider

that'll

at

least

do

some

initial

testing

and

have

that

data

so

you

can

take

it

to

maybe

somebody

else

that

you

find

as

a

provider
.

Sometimes

you

just

have

to

start

with

a

simple

Google

search
.

Speaker 2
41:49

Yeah

which

can

also

be

scary
.

Speaker 1
41:53

It

does
,

yeah
,

it

does
.

Speaker 2
41:54

That's

what

I

hate

that

we

even

have

to

say

that
.

But

it's

like

top

hormone

specialist
,

best

hormone

specialist

or

something

like

that
,

and

then

sift

through

it
.

Does

their

website

look

scammy
?

Speaker 1
42:04

Sometimes

you

need

to

go

to

three

different

ones

to

get

a

good

vibe
,

and

that's

OK
,

yeah

$500

consult
.

Speaker 2
42:11

Totally

OK
,

you're

not

going

to

miss

out

on

anything
.

Great

if

you

can't

afford

that
?

Speaker 1
42:14

No
,

no
,

there's

other

options

for

sure
.

Ok
,

thank

you

so

much

for

breaking

that

down

for

us
,

for

talking

about

that
,

because

I

think

it's

something

that

every

person
,

through

change

of

life

or

surgical

menopause
,

is

going

to

go

through

at

some

point
.

So

understanding

it

is

going

to

help

people

better

navigate

their

journey

and

making

sure

that

their

life

is

just

a

little

bit

easier

to

live

honestly
.

So

thank

you

so

much

for

taking

the

time
.

It's

always

great

to

talk

about

this

so

thank

you

so

much
.

Speaker 1
42:43

Thank

you

for

having

me
.

I

really

appreciate

it
.

Yes
,

and

until

next

time
,

continue

advocating

for

you

and

for

those

that

you

love
.

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